Ginger (Zingiber officinale), a common kitchen spice with a long history in traditional medicine, is now gaining attention for its potential to support those suffering from Inflammatory Bowel Disease (IBD), including conditions like Crohn’s disease and ulcerative colitis.
Recent research highlights that ginger’s powerful anti-inflammatory and antioxidant properties may help reduce inflammation in the gut and support intestinal healing. Its active compounds, particularly 6-gingerol and 6-shogaol, have been shown to suppress pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6—key drivers of inflammation in IBD. At the same time, ginger appears to increase levels of anti-inflammatory cytokines like IL-10, helping to calm overactive immune responses.
In addition to modulating inflammation, ginger also acts as an antioxidant, reducing oxidative stress in the digestive tract. Oxidative stress plays a significant role in the progression and flare-ups of IBD, so minimizing this damage can potentially improve symptoms and support long-term gut health.
Human trials so far are promising, with some patients reporting improvements in disease markers and quality of life. However, researchers emphasize the need for larger clinical studies to determine the best dosage and form of ginger for therapeutic use.
Most importantly, ginger is considered safe for most people, making it an accessible and natural option to explore as part of a holistic IBD management plan—always with your healthcare provider’s guidance.
Reference:
Zingiber officinale (Ginger) as a Treatment for Inflammatory Bowel Disease. Published in Frontiers in Drug Discovery.
Read the full article here: https://www.frontiersin.org/articles/10.3389/fddsv.2022.1043617/full
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